You are here:

Depressive Symptoms and Suicidality in Adolescents Using e-Cigarettes and Marijuana

posted 24/01/2019

publication Journal of Addiction Medicine doi: 10.1097/ADM.0000000000000506

Depressive Symptoms and Suicidality in Adolescents Using e-Cigarettes and Marijuana
A Secondary Data Analysis From the Youth Risk Behavior Survey

Chadi, Nicholas, MD; Li, Guilin, MBBS; Cerda, Natalie, MD; Weitzman, Elissa R., ScD, MSc

Journal of Addiction Medicine: January 24, 2019 - Volume Publish Ahead of Print - Issue - p
doi: 10.1097/ADM.0000000000000506

Author Information
Article Metrics

Objectives: E-cigarette use has increased dramatically among adolescents in the past 5 years alongside a steady increase in daily use of marijuana. This period coincides with a historic rise in depression and suicidal ideation among adolescents. In this study, we describe the associations between e-cigarette and marijuana use and depressive symptoms and suicidality in a large nationally representative sample of high school students.

Methods: We used data from the 2 most recent waves (2015 and 2017) of the Youth Risk Behavior Survey. Our sample (n = 26,821) included only participants with complete information for age, sex, race/ethnicity, and exposure to e-cigarettes and marijuana (89.5% of survey respondents). We performed multivariate logistic regressions to explore the associations between single or dual use of e-cigarette and marijuana and depressive and suicidal symptoms in the past year adjusting for relevant confounders.

Results: E-cigarette-only use was reported in 9.1% of participants, marijuana-only use in 9.7%, and dual e-cigarette/marijuana use in 10.2%. E-cigarette-only use (vs no use) was associated with increased odds of reporting suicidal ideation (adjusted odds ratio [AOR]:1.23, 95% CI 1.03–1.47) and depressive symptoms (AOR: 1.37, 95% CI 1.19–1.57), which was also observed with marijuana-only use (AOR: 1.25, 95% CI 1.04–1.50 and AOR: 1.49, 95% CI 1.27–1.75) and dual use (AOR: 1.28, 95% CI 1.06–1.54 and AOR: 1.62, 95% CI 1.39–1.88).

Conclusions: Youth with single and dual e-cigarette and marijuana use had increased odds of reporting depressive symptoms and suicidality compared to youth who denied use. There is a need for effective prevention and intervention strategies to help mitigate adverse mental health outcomes in this population.

get involved

If you are interested in what we do and would like to support our work, find out more ways to get involved.


get our book

Drugs: It’s just not worth it

Drugs: It’s just not worth it

Our 35-page book gives clear and easy to read facts and advice aimed at teenagers and young people.


Buy Now